시그니처 균주
BIFIDOBACTERIUM LACTIS HN019™
Grant JR, Stothard P. The CGView Server: a comparative genomics tool for circular genomes. Nucleic Acids Res. 2008;36:W181-W184.
소개
B. lactis HN019™는 수십 년 동안 유제품을 통해 섭취되어 왔으며, 프로바이오틱스 기능에 대해 111개 이상의 과학 논문에서 충분히 연구되었습니다. 이것은 산성 조건들을 견디는 것으로 확인되었으며, 인간 장을 통과하여 생존하는 것으로 나타났습니다.1-3 인체적용시험을 통해 HN019™가 대장 운동에 좋은 영향을 끼칠 수 있다는 것을 보여주며, 단독으로, 혹은 프리바이오틱스 및 기타 프로바이오틱스 균주들과 결합하여 HN019™를 연구한 다수의 인체적용시험들은 변이 잘 배설되지 않는 증상을 가진 사람들의 장 연동운동 촉진을 확인했습니다.4-6 또한 HN019™는 특히 노년층의 세포 면역 활동을 강화하며, 면역 기능을 조절하는 것으로 나타났습니다.7
건강 기능 분야
건강 기능 분야
지원되는 함량
지원되는 함량
2 billion to 17 billion HN019™/day
연구 참조
연구 참조
건강 기능 분야
건강 기능 분야
지원되는 함량
지원되는 함량
5 billion minimum HN019™/day
연구 참조
연구 참조
제품 기능성 연구들을 통한 21개의 In vitro 연구
참고문헌:
1. Gopal PK, Prasad J, Gill HS Effects of the consumption of Bifidobacterium lactis HN019 (DR10 TM) and galacto-oligosaccharides on the microflora of the gastrointestinal tract in human subjects. Nutrition Research. 2003;23:1313-1328. 2. Prasad J, Sazawal S, Dhingra U, Gopal PK Detection of viable Bifidobacterium lactis HN019 (DR10TM) in stools of children during a synbiotic dietary intervention trial. Intl Dairy J. 2013;30:64-67. 3. Wickens K, Black PN, Stanley TV, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clinical Immunology. 2008;122:788-794. 4. Dalziel JE, Anderson RC, Peters JS, et al. Promotility action of the probiotic Bifidobacterium lactis HN019™ extract compared with prucalopride in isolated rat large intestine. Frontiers in Neuroscience. 2017; 11. 5. Ibarra A, Latreille-Barbier M, Donazzolo Y, Pelletier X, Ouwehand AC. Effects of 28-day Bifidobacterium animalis subsp. lactis HN019™ supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled and dose-ranging trial. Gut Microbes. 2017; Dec 11:0. 6. Waller PA, Gopal PK, Leyer GJ, et al. Dose-response effect of Bifidobacterium lactis HN019™ on whole gut transit time and functional gastrointestinal symptoms in adults. Scandinavian J Gastroenterology. 2011;46:1057-1064. 7. Miller LE, Lehtoranta L, Lehtinen MJ. The Effect of Bifidobacterium animalis ssp. lactis HN019™ on cellular immune function in healthy elderly subjects: systematic review and meta-analysis. Nutrients. 2017;9:191.
1. Gopal PK, Prasad J, Gill HS Effects of the consumption of Bifidobacterium lactis HN019 (DR10 TM) and galacto-oligosaccharides on the microflora of the gastrointestinal tract in human subjects. Nutrition Research. 2003;23:1313-1328. 2. Prasad J, Sazawal S, Dhingra U, Gopal PK Detection of viable Bifidobacterium lactis HN019 (DR10TM) in stools of children during a synbiotic dietary intervention trial. Intl Dairy J. 2013;30:64-67. 3. Wickens K, Black PN, Stanley TV, et al. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial. J Allergy Clinical Immunology. 2008;122:788-794. 4. Dalziel JE, Anderson RC, Peters JS, et al. Promotility action of the probiotic Bifidobacterium lactis HN019™ extract compared with prucalopride in isolated rat large intestine. Frontiers in Neuroscience. 2017; 11. 5. Ibarra A, Latreille-Barbier M, Donazzolo Y, Pelletier X, Ouwehand AC. Effects of 28-day Bifidobacterium animalis subsp. lactis HN019™ supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled and dose-ranging trial. Gut Microbes. 2017; Dec 11:0. 6. Waller PA, Gopal PK, Leyer GJ, et al. Dose-response effect of Bifidobacterium lactis HN019™ on whole gut transit time and functional gastrointestinal symptoms in adults. Scandinavian J Gastroenterology. 2011;46:1057-1064. 7. Miller LE, Lehtoranta L, Lehtinen MJ. The Effect of Bifidobacterium animalis ssp. lactis HN019™ on cellular immune function in healthy elderly subjects: systematic review and meta-analysis. Nutrients. 2017;9:191.
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