HOWARU® Dophilus containing Lactobacillus acidophilus NCFM® is scientifically proven to reduce colonic transit time and relieve digestive discomfort.

The clinical study published on Pediatrics in 2008 to show consumption of probiotics would be able to reduce symptoms of respiratory tract infections. Children aged 3 to 5 years were recruited and randomly assigned to 1 of 3 groups to receive placebo (n = 92), Lactobacillus acidophilus NCFM® (NCFM® ) (n = 77), or a combination of L. acidophilus NCFM® and Bifidobacterium lactis Bi-07® (NCFM® +Bi-07® ) (n = 79). Probiotics were consumed daily at a dose of 1010 colony-forming units for 6 months from November to April. The study was performed in Shanghai, China, and approved by the local authorities.

Statistics showed that the incidence of fever was reduced by 63% in the NCFM® +Bi-07® group and by 48% in the NCFM® group. Cough was reduced by 54% in the NCFM® +Bi-07® group and by 42% in the NCFM® group. Runny nose was reduced by 44% in the NCFM® +Bi-07® group and by 9% in the NCFM® group; the latter result was not significant. Antibiotic use was reduced by 80% in the NCFM® +Bi-07® group and by 68% in the NCFM® group. Children in the placebo group had, on average, 6.5 days with symptoms, those in the NCFM® group had 4.5 days with symptoms, and those in the NCFM® +Bi-07® group had 3.4 days with symptoms.