DuPont Nutrition & Health and Lonza Specialty Ingredients Announce Joint Agreement in Human Milk Oligosaccharides | HOWARU® | Clinically-Mastered Probiotics

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DuPont Nutrition & Health and Lonza Specialty Ingredients Announce Joint Agreement in Human Milk Oligosaccharides

High Quality Human Milk Oligosaccharide, CARE4U™ 2’-FL to respond to the Rising Global Demand for Infant Nutrition Products

COPENHAGEN, Denmark, Feb. 27, 2019 – DuPont Nutrition & Health and Lonza Specialty Ingredients announce an agreement under which the leading biotechnology and specialty ingredient company Lonza will manufacture and supply CARE4U™ 2’-FL – a human milk oligosaccharide (HMOs). This strategic manufacturing collaboration reinforces market confidence in the supply and premium quality of this specialty ingredient.

DuPont Nutrition & Health is a world leader in microbial technology, health and nutrition, and the development of HMOs is part of a larger microbiome investment strategy for DuPont and central to this is developing scalable production methods.

“By engaging strategically with Lonza, DuPont will be able to accelerate commercialization and offer high-quality HMOs to customers and prospects. The collaboration with Lonza will play a key role in DuPont’s business growth strategy by focusing on providing high-quality consumer health and wellness products,” said John Rea, Global Business Unit Leader, Cultures, Probiotics, Food Protection, HMO & Fibers, DuPont Nutrition & Health.

Lonza is a leading integrated solutions provider to the global consumer health care, pharmaceutical, nutrition, and personal care industries with a comprehensive portfolio of proprietary nutritional ingredients, innovative formulation and delivery technologies and a strong platform in biotechnology. Lonza has been manufacturing high-quality products since 1897 and now has 50 major manufacturing sites that span the globe.

“Partnering with DuPont, Lonza will apply its leading science and biotechnology expertise in consumer health and nutrition applications to develop and manufacture superior quality human milk oligosaccharide CARE4U™ 2’-FL,” said Erasmo Schutzer, President of Lonza’s Consumer Health Division.

Naturally present in human milk, human milk oligosaccharides (HMOs) have been shown to support digestive, immune and cognitive development in infants by modifying the gut microbiota. Infant formula attempts to mimic the nutritional composition of breast milk as closely as possible, and clinical studies have shown that CARE4U™ 2’-FL can mimic some of the health-promoting effects of HMOs. CARE4U™ 2’-FL is produced by microbial fermentation and the final product contains more than 98 percent 2’-fucosyllactose, the most abundant of the more than 130 oligosaccharides in human milk. This makes CARE4U™ 2’-FL one of the purest human milk oligosaccharide products

on the market today. Superior powder properties (high purity and density) of CARE4U™ 2’-FL make it easy to use in infant formula and dietary supplements.

With ever increasing world population there is likely to be an increased and growing demand for infant nutrition products including HMOs for infant formula. Through the agreement with Lonza, DuPont Nutrition & Health will obtain a significant volume and high quality, reliable supply chain to be able to provide functional human milk oligosaccharide 2-fucosyllactose (2’-FL) for these growing global markets.

For more information about CARE4U™ 2’-FL, visit https://www.dupontnutritionandhealth.com/product-range/hmos.html.

about Lonza Howaru

About Lonza

Lonza is an integrated solutions provider that creates value along the Healthcare Continuum®. Through our Lonza Pharma Biotech & Nutrition segment and our Lonza Specialty Ingredients segment businesses, we harness science and technology to serve markets along this continuum. We focus on creating a healthy environment, promoting a healthier lifestyle and preventing illness through consumers’ preventive healthcare, as well as improving patient healthcare by supporting our customers to deliver innovative medicines that help treat or even cure severe diseases.

Patients and consumers benefit from our ability to transfer our pharma know-how to the healthcare, hygiene and fast-moving consumer goods environment and to the preservation and protection of the world where we live.
Founded in 1897 in the Swiss Alps, Lonza today is a well-respected global company with more than 100 sites and offices and approximately 15,500 full-time employees worldwide at the end of 2018. The company generated sales of CHF 5.5 billion in 2018 with a CORE EBITDA of CHF 1.5 billion. Further information can be found atwww.lonza.com.

About DuPont Nutrition & Health

DuPont Nutrition & Health, a DowDuPont Specialty Products Division business, combines in-depth knowledge of food and nutrition with current research and expert science to deliver unmatched value to the food, beverage, pharmaceutical and dietary supplement industries. We are innovative solvers, drawing on deep consumer insights and a broad product portfolio to help our customers turn challenges into high-value business opportunities. More information is available at www.food.dupont.com.

About DowDuPont Specialty Products Division

DowDuPont Specialty Products, a division of DowDuPont (NYSE: DWDP), is a global innovation leader with technology-based materials, ingredients and solutions that help transform industries and everyday life. Our employees apply diverse science and expertise to help customers advance their best ideas and deliver essential innovations in key markets including electronics, transportation, building and construction, health and wellness, food and worker safety. DowDuPont intends to separate the Specialty Products Division, which will be called DuPont, into an independent, publicly traded company. More information can be found at www.dow-dupont.com.

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The DuPont Oval logo, DuPont™ and all products, unless otherwise noted, denoted with ™, or ® are trademarks or registered trademarks of E.I. du Pont de Nemours and Company or its affiliates.

For further information contact:

DuPont Nutrition & Health Lonza

Richard Donovan
+33-6-71-58-98-54

richard.donovan@dupont.com

Constance Ward

+41-61-316-8840

constance.ward@lonza.com